Alvin Kamara : 35 rush(es) for 333 yards Tarik Cohen : 9 rush(es) for 182 yards Derrick Henry : 4 rush(es) for 140 yards Mark Ingram : 19 rush(es) for 138 yards Dion Lewis : 17 rush(es) for 127 yards Lamar Jackson : 19 rush(es) for 100 yards Devonta Freeman : 10 rush(es) for 93 yards Marcus Mariota : 8 rush(es) for 91 yards Dak Prescott : 11 rush(es) for 65 yards Isaiah Crowell : 5 rush(es) for 62 yards Jamaal Williams : 4 rush(es) for 57 yards Matt Breida : 11 rush(es) for 56 yards Todd Gurley : 14 rush(es) for 44 yards C. Mccaffrey : 12 rush(es) for 43 yards Deshaun Watson : 5 rush(es) for 39 yards Alex Collins : 15 rush(es) for 33 yards Adrian Peterson : 10 rush(es) for 32 yards Josh Mccown : 2 rush(es) for 22 yards Jameis Winston : 4 rush(es) for 13 yards Blake Bortles : 2 rush(es) for 13 yards Sony Michel : 3 rush(es) for 9 yards Alex Smith : 2 rush(es) for 7 yards Josh Allen : 2 rush(es) for 6 yards B Roethlisberger : 2 rush(es) for 6 yards Rex Burkhead : 1 rush(es) for 2 yards